Scientist I, Analytical Development - Cambridge, MA Job at Hydrogen Group, Cambridge, MA

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  • Hydrogen Group
  • Cambridge, MA

Job Description

Location: Cambridge, MA (100% onsite)


Schedule: Standard Office Hours (40 hours per week)


Duration: 6-Month Contract, extension/conversion potential


Pay Rate: $38.00/ph - $42.00/ph


This role will support the development of small molecule and oligonucleotide drug substances and drug products by advancing analytical technologies and establishing control strategies. The selected candidate will focus on chromatographic method development, applying analytical quality by design (AQbD) principles and predictive modeling.


A strong foundation in organic chemistry, analytical chemistry, and hands-on laboratory experience is essential. Proficiency in analytical techniques such as UV spectroscopy, HPLC/UPLC, and LCMS is also required.

Key Responsibilities:

Design, execute, and document experiments under the guidance of a manager.


Develop and optimize analytical methods using HPLC/UPLC systems.


Design AQbD experiments and leverage experimental data for chromatographic separation modeling.


Perform sample analysis using HPLC/UPLC with UV or MS detection.


Analyze and interpret data, write technical reports, and establish protocols.


Stay informed on advancements in therapeutic small molecule and oligonucleotide development by attending relevant meetings and seminars.

Qualifications:

Fundamental lab skills, including pipetting, solution preparation, and centrifugation.


Hands-on experience with HPLC/UHPLC systems and related software.


Strong understanding of liquid chromatography (LC) separation principles.


Familiarity with LCMS is preferred.


Experience in analytical method development for pharmaceuticals is a plus.


Proficiency in documentation practices, data analysis, reporting, and review.


Ability to quickly learn new methods and demonstrate scientific curiosity and innovation.


Strong oral and written communication skills.

Education:

MS or PhD in chemistry, biochemistry, chemical engineering, pharmaceutical sciences, or a related field.


...

Job Tags

Contract work,

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